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Along with their useful effects Esomeprazole can cause unwanted side effects, which usually improve as your body adjusts to the new medicine. If taken on an empty stomach at least one hour before meals, swallowed whole and shouldn't be crushed or chewed. Esomeprazole is used to treat the infection that causes ulcers occurring just beyond the exit from the stomach. If you buy any medicines check with a pharmacist that they are safe to take with Esomeprazole. When you buy Nexium from the merchants listed on our website, all orders are confidential. There are no restrictions on food, beverages, or activities while taking Nexium, unless otherwise directed by your doctor.