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Prednisone is used in the management of adrenal insufficiency unless a more potent mineral corticoid is administered concomitantly. Prednisolone is a corticosteroid used to treat various inflammatory and allergy conditions as well as other diseases. Deltasone may not work as effectively in people with liver disease whose ability to convert prednisone to Prednisolone is impaired. Your steroid medication needs may change if you have any of these conditions, you may need a dose adjustment or special tests to safely take Prednisolone. Prednisone is used in much higher doses than the levels of corticosteroids produced naturally by the body.
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