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What should my health care professional know before I take Esomeprazole? For while taking Esomeprazole? Decreasing the acid produced by acid pumps. Esomeprazole works best if taken on an empty stomach at least one hour before meals, swallowed whole and shouldn't be crushed or chewed. Taking Nexium, unless otherwise directed by your doctor. You watch for while taking Esomeprazole? Esomeprazole reduce the production of acid in the stomach, Nexium reduces the amount of acid produced in the stomach.
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